PPREVALENCE OF COMPONENTS OF THE METABOLIC SYNDROME IN PATIENTS WITH ISCHEMIC HEART DISEASE IN YEREVAN POPULATION., ARMENIA

The research objective was aimed at the study of association of metabolic syndrome (MetS) and its components with coronary heart disease (CHD) among the population of Yerevan city (Armenia). Methods. During 2010-2011 in clinics of the Yerevan State Medical University and in the Center of preventive cardiology 320 patients with stable forms CHD (mean age 57.2±10.9 years) and 320 subjects without CHD (mean age 55.5± 11.7 years) were randomly selected. All patients have been surveyed according to current recommendations of clinical, instrumental and laboratory guidances. Diagnosis of MetS was defined by criteria AHA/NHLBI (2005). Biochemical analysis of blood made in hospital laboratories and anthropometrical indicators measured on standard procedures. Other data were obtained by use of the standard questionnaires. Study results were exposed to statistical processing by the parametric and nonparametric statistics methods, the zero hypothesis was rejected at p <0.05. Results. Obtained results indicated that among patients with CHD the blood plasma concentration of triglycerides (p<0.05) and systolic blood pressure (BP) (p<0.05) were considerably higher and waist circumference (p<0.001) as well was bigger in comparison with control group. The differences between indicators of high density lipoproteins and body mass index were not observed in both groups. High BP was the most frequent risk factor both in investigated and control groups (78% and 64% accordingly, p<0.001). By AHA/NHLBI criteria, prevalence of MetS amounted to 79.7% in investigated and 69.4% in control group, whereas the diabetes mellitus was more often observed in control group (27.1% against 15.5%). The authentic differences in prevalence of МetS between investigated and control groups were revealed only in combination of all components of МetS. In this respect significant difference between classifications of МetS according to AHA/NHLBI and IDF does not come to light. Conclusion. The prevalence of MetS was higher among patients with a CHD that was shown in full clusters. From practical point of view AHA/NHLBI and IDF criteria of a metabolic syndrome are equivalent.

метаболический синдром, ишемическая болезнь сердца, распространенность, Ереван, Армения, metabolic syndrome, coronary heart disease, prevalence, Yerevan, Armenia

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