Posterior wall isolation using the cryoballoon ablation in patients with persistent and long-standing persistent atrial fibrillation
A. S. Omelyanenko,
T. M. Uskach,
T. I. Mavludov,
A. R. Nasibullina,
D. F. Khaziakhmetov,
D. I. Cherkashin,
D. F. Ardus,
O. V. Sapelnikov https://doi.org/10.38109/2225-1685-2025-1-6-15
Abstract
Aim. To evaluate the efficacy and safety of posterior wall isolation using the cryoballoon ablation in patients with persistent and long-standing persistent forms of atrial fibrillation in comparison with pulmonary vein antrum cryoballoon isolation.
Methods. One hundred seventeen (n=117) patients with persistent (n=73) and long-standing persistent (n=44) atrial fibrillation, median left ventricular ejection fraction was 58,0% [54,0; 60,0]. The median size of the left atrial was 4,2 cm [4,00; 4,60]. A comparative analysis of the results of cryoballoon isolation supplemented with isolation of the posterior wall of the left atrium – group A (61 patients) and classic cryoballoon pulmonary vein antrum cryoballoon isolation – group B (56 patients) was performed.
Results. In one-year follow-up the efficacy of cryoballoon isolation supplemented with isolation of the posterior wall of the left atrium was significantly higher – 73,8% (n=45) than in cryoballoon pulmonary vein isolation – 67,9% (n=38) (p=0,030). There were no statistically significant differences in complication rates between the groups. No life-threatening complications were recorded during this study.
Conclusion. Both methods showed comparable safe results. Isolation of the posterior wall using cryoballoon in addition to pulmonary vein isolation is a more effective method of catheter treatment of persistent and long-persistent forms of atrial fibrillation in comparison with classic cryoballoon isolation of the atrial fibrillation.
About the Authors
A. S. Omelyanenko
Institute of Fundamental Medicine and Biology, Kazan Federal University
Russian Federation
Russian Federation
Anton S. Omelyanenko, Head of Surgical Department No. 3
18 Kremlevskaya street, Kazan 420008
T. M. Uskach
E.I. Chazov National Medical Research Centre of Cardiology
Russian Federation
Russian Federation
Tatiana M. Uskach, Dr. of Sc. (Med.), Professor, Leading Research Fellow, Department of Myocardial Diseases and Heart Failure
st. Academician Chazova, 15 a, Moscow 121552
T. I. Mavludov
Institute of Fundamental Medicine and Biology, Kazan Federal University
Russian Federation
Russian Federation
Timur I. Mavludov, Cardiovascular Surgeon
18 Kremlevskaya street, Kazan 420008
A. R. Nasibullina
Institute of Fundamental Medicine and Biology, Kazan Federal University
Russian Federation
Russian Federation
Aliya R. Nasibullina, Cardiologist
18 Kremlevskaya street, Kazan 420008
D. F. Khaziakhmetov
Institute of Fundamental Medicine and Biology, Kazan Federal University
Russian Federation
Russian Federation
Daniyar F. Khaziakhmetov, Cand. of Sc. (Med.), Associate Professor, Cardiovascular Surgeon
18 Kremlevskaya street, Kazan 420008
D. I. Cherkashin
E.I. Chazov National Medical Research Centre of Cardiology
Russian Federation
Russian Federation
Dmitriy I. Cherkashin, Cand. of Sc. (Med.), Senior Research, the Laboratory of Surgical and X-ray Surgical Methods for the Treatment of Cardiac Arrhythmias, Department of Cardiovascular Surgery
st. Academician Chazova, 15 a, Moscow 121552
D. F. Ardus
E.I. Chazov National Medical Research Centre of Cardiology
Russian Federation
Russian Federation
Darin F. Ardus, Cand. of Sc. (Med.), Junior researcher, the Laboratory of Surgical and X-ray Surgical Methods for the Treatment of Cardiac Arrhythmias, Department of Cardiovascular Surgery
st. Academician Chazova, 15 a, Moscow 121552
O. V. Sapelnikov
E.I. Chazov National Medical Research Centre of Cardiology
Russian Federation
Russian Federation
Oleg V. Sapelnikov, Dr. of Sci. (Med.), Chief Researcher, the Laboratory of Surgical and X-Ray Surgical Methods for the Treatment of Cardiac Arrhythmias, Department of Cardiovascular Surgery
st. Academician Chazova, 15 a, Moscow 121552
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Review
For citations:
Omelyanenko A.S., Uskach T.M., Mavludov T.I., Nasibullina A.R., Khaziakhmetov D.F., Cherkashin D.I., Ardus D.F., Sapelnikov O.V. Posterior wall isolation using the cryoballoon ablation in patients with persistent and long-standing persistent atrial fibrillation. Eurasian heart journal. 2025;(1):6-15. (In Russ.) https://doi.org/10.38109/2225-1685-2025-1-6-15
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