Adherence to antihypertensive therapy is a way to improve cardiovascular prognosis
https://doi.org/10.38109/2225-1685-2025-2-44-51
Abstract
High medical adherence is a prerequisite for achieving goals in the treatment of hypertension (HTN). This review describes the factors influencing adherence, ways of its assessment and methods of increasing medical adherence in hypertensive patients. The majority of patients with HTN showed low adherence to treatment, which requires finding ways to solve this problem. A number of studies demonstrated that single-pill combinations of antihypertensive drugs can make a significant contribution to solving such a complex problem as low adherence. The use of single-pill combinations (SPC) of antihypertensive drugs can be considered as one of the main and important tools for increasing adherence to antihypertensive therapy. Recently published data have been demonstrated that the triple SPC of amlodipine/indapamide/perindopril, compared with free combinations of the same components, already after one year of therapy helps to increase adherence to therapy and reduce the risk of cardiovascular outcomes and patient costs
Keywords
treatment adherence,
antihypertensive therapy,
fixed-dose combinations,
amlodipine/indapamide/perindopril
Supporting agencies: Manuscript was prepared with the Servier pharmaceutical company informational and financial support that did not impact on author’s opinion.
About the Authors
H. D. Kosmacheva
Research institute — Ochapovsky regional hospital no. 1; Kuban state medical university
Russian Federation
Russian Federation
Helen D. Kosmacheva, Dr. Of Sci. (Med.), Deputy Chief Physician for Medical Care, Head of the Department of Therapy no. 1; the Faculty of Advanced Training and Professional Retraining of Specialists
O. G. Kompaniets
Kuban state medical university
Russian Federation
Russian Federation
Olga G. Kompaniets, Cand. Of Sci. (Med.), Associate Professor, the Department of Therapy no. 1, the Faculty of Advanced Training and Professional Retraining of Specialists
G. G. Petrik
Kuban state medical university
Russian Federation
Russian Federation
Galina G. Petrik, Dr. Of Sci. (Med.), Professor of the Department of Therapy no. 1, the Faculty of Advanced Training and Professional Retraining of Specialist
A. О. Agafonova
Kuban state medical university
Russian Federation
Russian Federation
Anastasia О. Agafonova, 6th year medical student in the faculty of internal medicine
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Kosmacheva H.D., Kompaniets O.G., Petrik G.G., Agafonova A.О. Adherence to antihypertensive therapy is a way to improve cardiovascular prognosis. Eurasian heart journal. 2025;(2):44-51. (In Russ.) https://doi.org/10.38109/2225-1685-2025-2-44-51
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