Dynamics of social and labor status in patients undergoing pulmonary thromboendarterectomy
https://doi.org/10.38109/2225-1685-2023-4-16-22
Abstract
Aim. To study the dynamics of social and labor status in patients with chronic thromboembolic pulmonary hypertension (CTEPH) 6 months after pulmonary endarterectomy (PEA) and to identify clinical factors affecting the resumption of labor activity in the late postoperative period.
Material and methods. The study included 79 patients with CTEPH scheduled for PEA. The average age was 48.6 (39.3-59.4) years. We analyzed clinical and functional data, as well as social and labor status before and 6 months after PEA. Using multivariate regression analysis, the factors influencing the resumption of labor activity after PEA, were studied.
Results. In the general cohort of patients with CTEPH, 6 months after surgery, a slight increase in the proportion of working patients of all ages was revealed - from 55.7% to 65.8% (p=0.19). In the subgroup of patients of working age (61 people), the proportion of working patients in dynamics increased significantly – from 67.2 to 85.2% (p=0.03). Multivariate regression analysis showed a protective effect of the 2nd stage of rehabilitation on social and labor status after PEA – OR 4.2 (2.9-8.3 95%CI) (p=0.01). The presence of atrial fibrillation and residual pulmonary hypertension negatively affected the resumption of labor activity in the long-term period after PEA – OR 0.6 (0.3-0.9 95%CI) (p = 0.03) and OR 0.7 (0.2-0.8 95%CI) (p=0.01) respectively.
Conclusion. The dynamics of the social and labor status of patients with CTEPH 6 months after PEA is characterized by a significant increase in the proportion of working patients of working age from 67.2 to 85.2% compared with the preoperative level. The leading protective factor for the renewal of labor potential in patients with CTEPH within 6 months after PEE is the underwenting of the 2nd stage of rehabilitation. Residual pulmonary hypertension and atrial fibrillation are limiting factors for resuming of labor activity.
About the Authors
A. S. KlinkovaRussian Federation
Asya S. Klinkova, Cand. of Sci. (Med.), researcher, the Laboratory of Clinical Physiology, the Research Department of anesthesiology and critical care medicine
15 Rechkunovskaya street, Novosibirsk 630055
O. V. Kamenskaya
Russian Federation
Oksana V. Kamenskaya, Dr. of Sci. (Med.), Head of the Laboratory of Clinical Physiology, the Research Department of anesthesiology and critical care medicine
15 Rechkunovskaya street, Novosibirsk 630055
I. Y. Loginova
Russian Federation
Irina Y. Loginova, Cand. of Sci. (Biol.), researcher, the Laboratory of Clinical Physiology, the Research Department of anesthesiology and critical care medicine
15 Rechkunovskaya street, Novosibirsk 630055
S. S. Porotnikova
Russian Federation
Svetlana S. Porotnikova, researcher, the Laboratory of Clinical Physiology, the Research Department of anesthesiology and critical care medicine
15 Rechkunovskaya street, Novosibirsk 630055
A. G. Edemskiy
Russian Federation
Alexander G. Edemskiy, Cand. of Sci. (Med.), Cardiovascular surgeon, the cardiac surgery department of the aorta and coronary arteries
15 Rechkunovskaya street, Novosibirsk 630055
V. N. Lomivorotov
Russian Federation
Vladimir N. Lomivorotov, Dr. of Sci. (Med.), Professor, the training department
15 Rechkunovskaya street, Novosibirsk 630055
A. M. Chernyavskiy
Russian Federation
Aleksandr M. Chernyavskiy, Dr. of Sci. (Med.), Corresponding Member of RAS, Professor, general director
15 Rechkunovskaya street, Novosibirsk 630055
References
1. Kuzmichkina M.A., Serebryakova V.N. Rehabilitation of patients who underwent coronary bypass surgery from the point of view of restoring labor potential. Klinicheskaya meditsina. 2020;98(4):255263 (In Russ.)]. http://dx.doi.org/10.3062934651/0023-2149-2020-98-4-255-263
2. Chazova I.E., Martynyuk T.V., Valieva Z.S. et al. The economic burden of chronic thromboembolic pulmonary hypertension in the Russian. Terapevticheskii Arkhiv. 2018;90(9):101-109 (In Russ.)]. https://doi.org/10.26442/terarkh2018909101-109
3. Sagaydak O.V., Danilov N.M., Chazova I.E. Rehabilitation in patients with chronic thromboembolic pulmonary hypertension. Terapevticheskii Arkhiv. 2022;94(7):903–907 (In Russ.)]. https://doi.org/10.26442/00403660.2022.07.201735
4. Chazova I.E., Martynyuk T.V., Valieva Z.S. et al. Eurasian Guidelines for the diagnosis and treatment of chronic thromboembolic pulmonary hypertension (2020). Eurasian heart journal. 2021;(1):6-43 (In Russ.)]. https://doi.org/10.38109/2225-1685-2021-1-6-43
5. Kamenskaya O., Klinkova A., Chernyavskiy A. et al. Long-term health-related quality of life after surgery in patients with chronic thromboembolic pulmonary hypertension. Quality of Life Research. 2020;29(8):2111–8. http://dx.doi.org/10.1007/s11136-020-02471-z
6. Delcroix M., Torbicki A., Gopalan D. et al. ERS statement on chronic thromboembolic pulmonary hypertension. Eur Respir J. 2021;57(6):2002828. https://doi.org/10.1183/13993003.02828-2020
7. Choi J-W., Kim D-K., Kim J-K. et al. Age-adjusted Charlson comorbidity index v1. 2017; http://dx.doi.org/10.17504/protocols.io.mbzc2p6
8. S.M. Task force on surveillance for respiratory hazards in the occupational setting. Surveillance for respiratory hazards. ATS News. 1982 (8):12-16.
9. Polonskaya I.I., Sergeyeva V.V. Medical and social aspects of rehabilitation for coronary heart disease after coronary artery bypass grafting. The Bulletin of Contemporary Clinical Medicine. 2018;11(6):68-73. (In Russ.)]. https://doi.org/10.20969/VSKM.2018.11(6).68-73
10. La Rovere M.T., Pinna G.D., Pin M. et al. Exercise Training After Pulmonary Endarterectomy for Patients with Chronic Thromboembolic Pulmonary Hypertension. Respiration. 2019;97:1-8. https://doi.org/10.1159/000492754
11. An Q., Wang L., Yuan P. et al. Effectiveness and safety of exercise training and rehabilitation in chronic thromboembolic pulmonary hypertension: a systematic review and meta-analysis. Ann Palliat Med. 2021;10(7):8134-46. https://doi.org/10.21037/apm-21-1758
Review
For citations:
Klinkova A.S., Kamenskaya O.V., Loginova I.Y., Porotnikova S.S., Edemskiy A.G., Lomivorotov V.N., Chernyavskiy A.M. Dynamics of social and labor status in patients undergoing pulmonary thromboendarterectomy. Eurasian heart journal. 2023;(4):16-22. (In Russ.) https://doi.org/10.38109/2225-1685-2023-4-16-22