Vasoreactivity testing in pulmonary hypertension associated with congenital heart disease
https://doi.org/10.38109/2225-1685-2022-3-58-64
Abstract
In December, 2021 at the IXth All-Russian Congress «Pulmonary Hypertension 2021» the first Eurasian guidelines for the diagnosis and treatment of pulmonary hypertension associated with congenital heart disease in adults were approved. The expert group discussed many contentious issues, including the need for diagnostic tests for vasoreactivity. Invasive registration of the reaction of the pulmonary vessels to vasodilators – a vasoreactivity testing – in idiopathic, hereditary and drug- and toxin-induced pulmonary arterial hypertension (PAH) is used to determine indications for calcium antagonist therapy, in PAH associated with uncorrected congenital heart disease (CHD) in children – to determine the indications for surgical treatment. The use of a vasoreactivity testing to assess the operability of adult patients with congenital heart disease is inappropriate. An overview of the performance technique, specific pulmonary vasodilators and criteria for evaluating the test for vasoreactivity in various subgroups of PH associated with CHD is given.
About the Authors
A. A. Shmalts
A. N. Bakulev Scientific Center for Cardiovascular Surgery; Ministry of the Russian Federation
Russian Federation
Russian Federation
Anton A. Shmalts, Dr. of Sci. (Med.), Leading Research Associate, Associate Professor
Department of Cardiovascular Surgery
121552
Rublyevskoe Shosse 135
Russian State Medical Postgraduate Academy
123995
Barrikadnaya str., 2/1
Moscow
S. V. Gorbachevsky
A. N. Bakulev Scientific Center for Cardiovascular Surgery; Ministry of the Russian Federation
Russian Federation
Russian Federation
Sergej V. Gorbachevsky, Dr. of Sci. (Med.), Professor, Head of Department, Professor
Department of Cardiovascular Surgery
121552
Rublyevskoe Shosse 135
Russian State Medical Postgraduate Academy
123995
Barrikadnaya str., 2/1
Moscow
T. V. Martynyuk
E. I. Chazov National Medical Research Center of Cardiology; N. I. Pirogov Russian Medical Research Medical University
Russian Federation
Russian Federation
Tamila V. Martynyuk, Dr. of Sci. (Med.), Head of the Department, Professor
Department of Cardiology
121552
3rd Cherepkovskaya str., 15A
117997
Ostrovityanova str., 1
Moscow
S. N. Nakonechnikov
N. I. Pirogov Russian Medical Research Medical University, Russian Medical Society for Arterial Hypertension
Russian Federation
Russian Federation
Sergej N. Nakonechnikov, Dr. of Sci. (Med.), Professor, Director
Department of Cardiology
117997
Ostrovityanova str., 1
Moscow
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For citations:
Shmalts A.A., Gorbachevsky S.V., Martynyuk T.V., Nakonechnikov S.N. Vasoreactivity testing in pulmonary hypertension associated with congenital heart disease. Eurasian heart journal. 2022;(3):58-64. (In Russ.) https://doi.org/10.38109/2225-1685-2022-3-58-64
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