RELATIONSHIP OF BEHAVIORAL RISK FACTORS FOR CARDIOVASCULAR DISEASES AND ARTERIAL STIFFNESS IN WOMEN OF DIFFERENT AGE GROUPS WITH MEDICAL EDUCATION
https://doi.org/10.38109/2225-1685-2020-4-22-29
Abstract
Objective: to study the relationship of behavioral RF of CVD with arterial stiffness and daily dynamics of central aortic pressure in women of different age groups.
Materials and methods: 161 women were examined, which were divided into 3 groups: 1st group – 52 young women from 18 to 30 years old (23.8±5.3 years old); 2nd group – 54 women from 31 years old until menopause (41±5.9 years); Group 3 – 55 women in the postmenopausal period (55.4±5.8 years). All volunteers underwent questionnaires, anthropometry, the study of arterial stiffness with the Doppler method and the method of volume sphygmography, daily monitoring of blood pressure with an assessment of vascular stiffness and central aortic pressure.
Results: the strongest relationship between smoking and arterial stiffness was detected in the 3rd group, with the number of cigarettes per day being more important. Moderate alcohol consumption in group 1 is associated with an increase in the rate of increase in blood pressure in the aorta (dp / dt) max (R = 0.35, p = 0.01) and an improvement in the daily dynamics of central and peripheral pressure. A strict limitation of the caloric content of the consumed products is associated with a decrease in the carotidfemoral velocity of the cfSPV pulse wave (R = -0.2, p = 0.01) and an improvement in the characteristics of the reflected wave in all groups. Only in the 1st group, the use of 400 grams or more vegetables and fruits per day is associated with an improvement in rigidity. Low physical activity in the 3rd group is associated with an increase in the Weissler coefficient (R = 0.28, p = 0.04) and AASI (R = 0.29, p = 0.03).
Conclusion: behavioral RF of CVDs are interrelated with various indicators of arterial stiffness and changes in central and peripheral pressure in women of different ages. The most significant indicators can be used as markers for the development of subclinical changes in the vascular wall in women, depending on their risk factors in order to start preventive measures in a timely manner.
About the Authors
O. S. Ivanova
Moscow State University of Medicine and Dentistry
Russian Federation
Russian Federation
Postgraduate student of the Department of Hospital Therapy 1
Delegatskaya St., 20, p. 1, Moscow, Russian Federation, 127473
SPIN code: 8726-3309, AuthorID: 1053645
E. Y. Maychuk
Moscow State University of Medicine and Dentistry
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Professor of the Department of Hospital Therapy 1
Delegatskaya St., 20, p. 1, Moscow, Russian Federation, 127473
I. V. Voevodina
Moscow State University of Medicine and Dentistry
Russian Federation
Dr. of Sci. (Med.), Professor of the Department of Hospital Therapy 1
Delegatskaya St., 20, p. 1, Moscow, Russian Federation, 127473
Russian Federation
Dr. of Sci. (Med.), Professor of the Department of Hospital Therapy 1
Delegatskaya St., 20, p. 1, Moscow, Russian Federation, 127473
References
1. Piepoli M.F., Hoes A.W., Agewall S. et al. European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint ask Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts) Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Journal of Hypertension. 2016;37(29):2315-2381. https://doi:10.1093/eurheartj/ehw106
2. McEniery, CM. Yasmin, Maki-Petaja KM. et al. The impact of cardiovascular risk factors on aortic stiffness and wave reflections depends on age: the Anglo-Cardiff Collaborative Trial (ACCT III). Hypertension. 2010;56(4):591-597. https://doi:10.1161/HYPERTENSIONAHA.110.156950.
3. Vinokurova, G.I., Davidovich I.M., Voronova T.A. Vliyanie arterial`noj gipertenzii i kureniya na pokazateli zhyostkosti sosudistoj stenki u zhenshhin reproduktivnogo vozrasta. Problems of women’s health. 2011; 6 (4): 62 (in Russ.)
4. O’Neill D, Britton A, Brunner EJ et al. Twenty-Five-Year Alcohol Consumption Trajectories and Their Association With Arterial Aging: A Prospective Cohort Study. Journal of the American Heart Association. 2017;6(2):e005288. https://doi:10.1161/JAHA.116.005288
5. van den Elzen AP, Sierksma A, Oren A, et al. Alcohol intake and aortic stiffness in young men and women. Journal of Hypertension. 2005;23(4):731-735. https://doi:10.1097/01.hjh.0000163140.82212.16
6. Donato AJ, Machin DR, Lesniewski LA. Mechanisms of Dysfunction in the Aging Vasculature and Role in Age-Related Disease. Circulation Research. 2018;123(7):825-848. https://doi:10.1161/CIRCRESAHA.118.312563
7. Belsky DW, Huffman KM, Pieper CF, et al. Change in the Rate of Biological Aging in Response to Caloric Restriction: CALERIE Biobank Analysis. The Journals of Gerontology Series A Biological Sciences and Medical Sciences. 2017;73(1):4-10. https://doi:10.1093/gerona/glx096
8. Karimi L, Mattace-Raso FU, van Rosmalen J, et al. Effects of combined healthy lifestyle factors on functional vascular aging: the Rotterdam Study. Journal of Hypertension. 2016;34(5):853-859. https://doi:10.1097/HJH.0000000000000861
9. Petersen K, Blanch N, Keogh J, et al. Dietary Intake and Pulse Wave Velocity. Pulse (Basel). 2015;3(2):134-140. https://doi:10.1159/000435792
10. Bondonno CP, Croft KD, Hodgson JM. Dietary Nitrate, Nitric Oxide, and Cardiovascular Health. Critical Reviews in Food Science and Nutrition. 2016;56(12):2036-2052. https://doi:10.1080/10408398.2013.811212
11. Mills CE, Govoni V, Faconti L, et al. A randomised, factorial trial to reduce arterial stiffness independently of blood pressure: Proof of concept? The VaSera trial testing dietary nitrate and spironolactone. British Journal of Clinical Pharmacology. 2020;86(5):891-902. https://doi:10.1111/bcp.14194
12. Avolio AP, Clyde KM, Beard TC, et al. Improved arterial distensibility in normotensive subjects on a low salt diet. Arteriosclerosis. 1986;6(2):166-169. https://doi:10.1161/01.atv.6.2.166
13. Baldo MP, Brant LCC, Cunha RS, et al. The association between salt intake and arterial stiffness is influenced by a sex-specific mediating effect through blood pressure in normotensive adults: The ELSA-Brasil study. The Journal of Clinical Hypertension (Greenwich). 2019;21(12):1771-1779. https://doi:10.1111/jch.13728
14. Tanaka H, Tomoto T, Kosaki K, et al. Arterial stiffness of lifelong Japanese female pearl divers. American journal of physiology. Regulatory, integrative and comparative physiology. 2016;310(10):R975-R978. https://doi:10.1152/ajpregu.00048.2016
15. García-Hermoso A, Martínez-Vizcaíno V, Gomez-Marcos MÁ, et al. Ideal Cardiovascular Health and Arterial Stiffness in Spanish AdultsThe EVIDENT Study. Journal of Stroke and Cerebrovascular Diseases. 2018;27(5):1386-1394. https://doi:10.1016/j.jstrokecerebrovasdis.2017.12.031
Review
For citations:
Ivanova O.S., Maychuk E.Y., Voevodina I.V. RELATIONSHIP OF BEHAVIORAL RISK FACTORS FOR CARDIOVASCULAR DISEASES AND ARTERIAL STIFFNESS IN WOMEN OF DIFFERENT AGE GROUPS WITH MEDICAL EDUCATION. Eurasian heart journal. 2020;(4):22-29. (In Russ.) https://doi.org/10.38109/2225-1685-2020-4-22-29
Views:
432
Email this article 
