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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">evrazkar</journal-id><journal-title-group><journal-title xml:lang="ru">Евразийский Кардиологический Журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Eurasian heart journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2225-1685</issn><issn pub-type="epub">2305-0748</issn><publisher><publisher-name>Евразийская ассоциация кардиологов</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.38109/2225-1685-2025-3-78-84</article-id><article-id custom-type="elpub" pub-id-type="custom">evrazkar-6539</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Современные проблемы клапанных кондуитов у детей с сердечно-сосудистыми заболеваниями</article-title><trans-title-group xml:lang="en"><trans-title>Modern problems of valvular conduits in children with cardiovascular diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-3193-4160</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Амансахатова</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Amansakhatova</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Амансахатова Екатерина Назаровна, стажер-исследователь; студент </p><p> ул. Пирогова, дом 1, г. Новосибирск 630090 </p></bio><bio xml:lang="en"><p>Ekaterina N. Amansakhatova, Researcher intern, Meshalkin National Medical Research Center; Student </p><p>1 Pirogova St., Novosibirsk 630090 </p></bio><email xlink:type="simple">amansakhatova_e@meshalkin.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1763-9535</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ничай</surname><given-names>Н. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Nichay</surname><given-names>N. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ничай Наталья Романовна, к.м.н., научный сотрудник, врач сердечно-сосудистый хирург, кардиохирургическое отделение №1; ассистент кафедры сердечно-сосудистой хирургии, факультет повышения квалификации и профессиональной переподготовки врачей </p><p>г. Новосибирск </p></bio><bio xml:lang="en"><p>Nataliya R. Nichay, Cand. of Sci. (Med.), Researcher, Cardiovascular Surgeon, Cardiosurgical Department No. 1; Assistant Professor, Department of Cardiovascular Surgery, Faculty of Advanced Training and Professional Retraining of Doctors </p><p>Novosibirsk </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2361-5847</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулябин</surname><given-names>Ю. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulyabin</surname><given-names>Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кулябин Юрий Юрьевич, к.м.н., научный сотрудник, врач сердечно-сосудистый хирург, кардиохирургическое отделение №1 </p><p> г. Новосибирск </p></bio><bio xml:lang="en"><p>Yury Yu. Kulyabin, Cand. of Sci. (Med.), Researcher, Cardiovascular Surgeon, Cardiosurgical Department No. 1 </p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8935-4216</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Магбулова</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Magbulova</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Магбулова Сайхуна Ахмадовна, аспирант, врач сердечно-сосудистый хирург, кардиохирургическое отделение №1 </p><p> г. Новосибирск </p></bio><bio xml:lang="en"><p>Saihuna A. Magbulova, Postgraduate, Cardiovascular Surgeon, Cardiosurgical Department No. 1 </p><p>Novosibirsk </p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3691-2848</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сойнов</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Soynov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сойнов Илья Александрович, д.м.н., заведующий, научно-исследовательский отдел врожденных пороков сердца, врач сердечно-сосудистый хирург, кардиохирургическое отделение №1 </p><p> г. Новосибирск </p></bio><bio xml:lang="en"><p>Ilya A. Soynov, Dr. of Sci. (Med.), Head of the Research Department of Congenital heart defects, Cardiovascular Surgeon, Cardiosurgical Department No. 1 </p><p>Novosibirsk </p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ им. ак. Е.Н. Мешалкина» Минздрава России; ФГАОУ ВО «Новосибирский национальный исследовательский государственный университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ им. ак. Е.Н. Мешалкина» Минздрава России; ФГБОУ ВО «НГМУ» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Meshalkin National Medical Research Center; Novosibirsk State Medical&#13;
University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ им. ак. Е.Н. Мешалкина» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Meshalkin National Medical Research Center, Novosibirsk</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ им. ак. Е.Н. Мешалкина» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Meshalkin National Medical Research Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>25</day><month>09</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>78</fpage><lpage>84</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Амансахатова Е.Н., Ничай Н.Р., Кулябин Ю.Ю., Магбулова С.А., Сойнов И.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Амансахатова Е.Н., Ничай Н.Р., Кулябин Ю.Ю., Магбулова С.А., Сойнов И.А.</copyright-holder><copyright-holder xml:lang="en">Amansakhatova E.N., Nichay N.R., Kulyabin Y., Magbulova S.A., Soynov I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.heartj.asia/jour/article/view/6539">https://www.heartj.asia/jour/article/view/6539</self-uri><abstract><p>Аномалия выводного отдела правого желудочка у детей раннего возраста может встречаться как изолированно, так и охватывать группу врожденных пороков сердца. Такие пациенты с самого раннего возраста нуждаются в проведении радикальной коррекции порока, одним из элементов которого является формирование пути оттока из правого желудочка в легочную артерию. Несмотря на большое разнообразие клапанных протезов и клапансодержащих кондуитов на мировом рынке (легочный аллографт (CryoLife, USA), ксенокондуиты Contegra (Medtronic Inc., Minneapolis, MN), Freestyle (Medtronic Inc., Minneapolis, MN), кондуит из ePTFE (W.L. Gore &amp; Associates Inc, Flagstaff, AZ, USA), DP-BYVC (Yaxin Medical Technology Co., Ltd., Wuhan, China), на сегодняшний день нет идеального графта, который бы имел свободу от репротезирования. Проблема выбора оптимального кондуита для реконструкции выводного отдела правого желудочка остается актуальной, поскольку одной из ряда причин развития дисфункции кондуита ПЖ-ЛА является отсутствие способности роста по мере роста ребенка. Однако развитие тканеинженерных технологий в сердечно-сосудистой хирургии могут привести к разработке новых клапансодержащих кондуитов (Xeltis, Xeltis-XPC), которые могут стать достойной альтернативой существующих кондуитов для реконструкции ВОПЖ-ЛА и снизить количество реопераций в группе пациентов с аномалией выводного отдела ПЖ.</p></abstract><trans-abstract xml:lang="en"><p>Right ventricular outflow tract anomaly in young children can occur both in isolation and as part of a group of congenital heart defects. Such patients require radical correction of the defect from an early age, one of the elements of which is the formation of an outflow tract from the right ventricle to the pulmonary artery. Despite the wide variety of valve prostheses and valve-containing conduits on the world market (pulmonary allograft (CryoLife, USA), xenoconduits Contegra (Medtronic Inc., Minneapolis, MN), Freestyle (Medtronic Inc., Minneapolis, MN), ePTFE conduit (W.L. Gore &amp; Associates Inc, Flagstaff, AZ, USA), DP-BYVC (Yaxin Medical Technology Co., Ltd., Wuhan, China)), there is currently no ideal graft that would be free from repeated prosthetics. The problem of choosing the optimal conduit for the reconstruction of the right ventricular outflow tract remains relevant, since one of a number of reasons for the development of RVPA conduit dysfunction is the lack of growth ability as the child grows. However, the development of tissue engineering technologies in cardiovascular surgery may lead to the development of new valve-containing conduits (Xeltis, XeltisXPC), which may become a worthy alternative to existing conduits for RVOT-PA reconstruction and reduce the number of reoperations in the group of patients with RV outflow tract anomalies.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>врожденный порок сердца</kwd><kwd>легочный графт</kwd><kwd>клапансодержаший кондуит</kwd><kwd>тканеинженерный клапанный протез</kwd></kwd-group><kwd-group xml:lang="en"><kwd>congenital heart defect</kwd><kwd>pulmonary graft</kwd><kwd>valve-containing conduit</kwd><kwd>tissue-engineered valve prosthesis</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Данная работа выполнена в рамках государственного задания Минздрава России № 124022500251-0</funding-statement><funding-statement xml:lang="en">The research was carried out within the framework of the state assignment of the Ministry of Health of the Russian Federation (No. 124022500251-0).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Wu W., He J., Shao X. 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