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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">evrazkar</journal-id><journal-title-group><journal-title xml:lang="ru">Евразийский Кардиологический Журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Eurasian heart journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2225-1685</issn><issn pub-type="epub">2305-0748</issn><publisher><publisher-name>Евразийская ассоциация кардиологов</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.38109/2225-1685-2024-1-116-125</article-id><article-id custom-type="elpub" pub-id-type="custom">evrazkar-6449</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Желудочковая экстрасистолия: новые возможности диагностики и тактики ведения</article-title><trans-title-group xml:lang="en"><trans-title>Premature ventricular complexes: new possibilities of diagnostics and management</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0264-2686</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кужель</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzhel</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кужель Дмитрий Анатольевич, д.м.н., заведующий отделением функциональной диагностики, КГБУЗ «Красноярская краевая больница №2»; доцент</p><p>Ул. Карла Маркса, д. 43, г. Красноярск, 660049</p></bio><bio xml:lang="en"><p>Dmitriy A. Kuzhel, Dr. of Sci. (Med.), Chief of department functional diagnostics, Regional state hospital №2; associate professor, Professor </p><p>Partizan Zheleznyak str. 1, Krasnoyarsk 660022</p><p>Karl Marx str. 43, Krasnoyarsk 660049</p></bio><email xlink:type="simple">dakushel@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4438-1434</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Савченко</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Savchenko</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Савченко Елена Александровна, к.м.н., доцент</p><p>Ул. Партизана Железняка, д. 1, г. Красноярск, 660022</p></bio><bio xml:lang="en"><p>Elena A. Savchenko, Cand. of Sci. (Med.), associate professor, Professor</p><p>Partizan Zheleznyak str. 1, Krasnoyarsk 660022</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Красноярский Государственный медицинский университет имени профессора В.Ф. Войно-Ясенецкого» Министерства здравоохранения Российской Федерации; КГБУЗ «Красноярская краевая больница №2»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; Regional state hospital №2</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Красноярский Государственный медицинский университет имени профессора В.Ф. Войно-Ясенецкого» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>12</day><month>03</month><year>2024</year></pub-date><volume>0</volume><issue>1</issue><fpage>116</fpage><lpage>125</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кужель Д.А., Савченко Е.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Кужель Д.А., Савченко Е.А.</copyright-holder><copyright-holder xml:lang="en">Kuzhel D.A., Savchenko E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.heartj.asia/jour/article/view/6449">https://www.heartj.asia/jour/article/view/6449</self-uri><abstract><p>Желудочковая экстрасистолия (ЖЭ) является одним из наиболее часто встречающихся нарушений ритма в повседневной клинической практике. В подавляющем большинстве случаев ЖЭ имеет хороший прогноз, однако в некоторых случаях может служить причиной серьезных, в том числе и угрожаемых жизни осложнений. С другой стороны, бессимптомная, частая ЖЭ может приводить к развитию систолической дисфункции левого желудочка (ЛЖ), которая может быть обратима при эффективной терапии. Оплотом терапии ЖЭ остаются лекарственные препараты. Однако эффективность одних препаратов достаточно низкая, тогда как другие препараты имеют существенные побочные и проаритмические эффекты. Технологические достижения в области радиочастотной абляции (РЧА) в последние годы открыли огромные перспективы в радикальной коррекции ЖЭ и выдвигают этот подход в селективных случаях как метод выбора. Однако данная инвазивная технология может в то же время нести риски серьезных осложнений, которые могут наблюдаться у до 5% лиц, подвергнутых этой процедуре. Потенциальные риски РЧА во многом зависят от доступности эктопического очага. В этой связи важное значение приобретает дифференциальная диагностика источника эктопии для взвешенной оценки возможных рисков и эффективности этого инвазивного метода. Стандартные методы диагностики, такие как ЭКГ в 12 отведениях, холтеровское мониторирование и эхокардиография, позволяют во многих случаях принять оптимальное решение относительно дальнейшей тактики ведения. Частая, бессимптомная ЖЭ в случае высоких рисков осложнений при проведении РЧА и неэффективности лекарственной терапии в целях предотвращения развития систолической дисфункции ЛЖ требует ежегодного мониторинга с помощью как традиционных ультразвуковых методов, так и с применением новых технологий оценки функционального состояния миокарда.</p></abstract><trans-abstract xml:lang="en"><p>Premature ventricular complexes (PVC) is one of the most common arrhythmias in daily clinical practice. In the vast majority of cases, PVC has a good prognosis, but in some cases it can cause serious, including lifethreatening complications. On the other hand, asymptomatic, frequent PVC can lead to the development of left ventricular (LV) systolic dysfunction, which can be reversible with effective therapy. Medications remain the mainstay of therapy for PVC. However, the effectiveness of some drugs is quite low, while other drugs have significant side and proarrhythmic effects. Technological advances in the field of radiofrequency (RF) catheter ablation in recent years have opened up tremendous prospects in the radical correction of PVC and put forward this approach in selective cases as the method of choice. However, this invasive technology may at the same time carry the risks of serious complications, which can occur in up to 5% of individuals undergoing this procedure. The potential risks of RF catheter ablation largely depend on the accessibility of the ectopic focus. In this regard, differential diagnosis of the source of ectopia is of great importance for a balanced assessment of the possible risks and effectiveness of this invasive method. Standard diagnostic methods, such as 12-lead electrocardiography, Holter monitoring and echocardiography, allow in many cases to make the best decision regarding further management tactics. Frequent, asymptomatic PVC needs in annual monitoring to prevent LV systolic dysfunction development in cases high potential RF catheter ablation risks and drugs ineffectiveness. Traditional echocardiography and novel ultrasound technologies can help in this difficult of choice cases.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>желудочковая экстрасистолия</kwd><kwd>сердечная недостаточность</kwd><kwd>радиочастотная абляция</kwd><kwd>эхокардиография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>premature ventricular complexes</kwd><kwd>heart failure</kwd><kwd>radiofrequency catheter ablation</kwd><kwd>echocardiography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ganesananthan S., Rajkumar C.A., Foley M., et al. Remote digital smart device follow-up in prospective clinical trials: early insights from ORBITA-2, ORBITA-COSMIC, and ORBITA-STAR. Eur Heart J Suppl. 2022;24(Suppl H):H32-H42. https://doi.org/10.1093/eurheartjsupp/suac058</mixed-citation><mixed-citation xml:lang="en">Ganesananthan S., Rajkumar C.A., Foley M., et al. 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