evrazkarЕвразийский Кардиологический ЖурналEurasian heart journal2225-16852305-0748Евразийская ассоциация кардиологов10.38109/2225-1685-2023-4-32-40evrazkar-6424Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИORIGINAL PAPERSВоспроизводимость ангиокорегистрации моментального резерва кровотока у больных ИБС с диффузным и многоуровневым поражением коронарных артерийReproducibility of instantaneous wave-free ratio and angiography coregistration in patients with coronary heart disease and diffuse and multilevel coronary artery lesionhttps://orcid.org/0000-0003-1538-2761БубновД. С.BubnovD. S.

Бубнов Дмитрий Сергеевич, младший научный сотрудник, лаборатория рентгенэндоваскулярных методов диагностики и лечения в амбулаторных условиях

ул. Академика Чазова, д. 15 а, г. Москва 121552

Dmitry S. Bubnov, Junior Researcher, Head of the Laboratory of endovascular methods of diagnosis and treatment on an outpatient basis

Ac. Chazov street, 15 a, Moscow 121552

bubnowdima@mail.ruhttps://orcid.org/0000-0003-3522-9537АтанесянР. В.AtanesyanR. V.

Атанесян Руслан Вагифович, к.м.н., научный сотрудник, лаборатория рентгенэндоваскулярных методов диагностики и лечения в амбулаторных условиях

ул. Академика Чазова, д. 15 а, г. Москва 121552

Ruslan V. Atanesyan, Cand. of Sci. (Med.),Researcher, Head of the Laboratory of endovascular methods of diagnosis and treatment on an outpatient basis

Ac. Chazov street, 15 a, Moscow 121552

atarus@bk.ruhttps://orcid.org/0000-0001-9739-6432КарданахишвилиЗ. Б.KardanakhishviliZ. B.

Карданахишвили Зураб Бесикиевич, к.м.н., научный сотрудник, лаборатория рентгенэндоваскулярных методов диагностики и лечения в амбулаторных условиях

ул. Академика Чазова, д. 15 а, г. Москва 121552

Zurab B. Kardanakhishvili, Cand. of Sci. (Med.),Researcher, Head of the Laboratory of endovascular methods of diagnosis and treatment on an outpatient basis

Ac. Chazov street, 15 a, Moscow 121552

kachelo1981@gmail.comhttps://orcid.org/0000-0003-4369-1393АгеевФ. Т.AgeevF. T.

Агеев Фаиль Таипович, д.м.н., профессор, главный научный сотрудник, отдел амбулаторных лечебно-диагностических технологий, Институт клинической кардиологии им. А.Д. Мясникова

ул. Академика Чазова, д. 15 а, г. Москва 121552

Fail’ T. Ageev, Dr. of Sci. (Med.), Chief Researcher, Head of the Department of Outpatient Diagnostic and Treatment Technologies, A.L. Myasnikov Research Institute of Clinical Cardiology

Ac. Chazov street, 15 a, Moscow 121552

ftageev@gmail.comhttps://orcid.org/0000-0002-0200-852XМатчинЮ. Г.MatchinYu. G.

Матчин Юрий Георгиевич, д.м.н., главный научный сотрудник, лаборатория рентгенэндоваскулярных методов диагностики и лечения в амбулаторных условиях

ул. Академика Чазова, д. 15 а, г. Москва 121552

Yuriy G. Matchin, Dr. of Sci. (Med.), Chief Researcher, Head of the Laboratory of endovascular methods of diagnosis and treatment on an outpatient basis

Ac. Chazov street, 15 a, Moscow 121552

yumatchin@gmail.comФГБУ «НМИЦ кардиологии им. Е.И. Чазова» Минздрава РоссииРоссияE.I. Chazov National Medical Research Center of CardiologyRussian Federation202322112023043240Copyright © Бубнов Д.С., Атанесян Р.В., Карданахишвили З.Б., Агеев Ф.Т., Матчин Ю.Г., 20232023Бубнов Д.С., Атанесян Р.В., Карданахишвили З.Б., Агеев Ф.Т., Матчин Ю.Г.Bubnov D.S., Atanesyan R.V., Kardanakhishvili Z.B., Ageev F.T., Matchin Y.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.heartj.asia/jour/article/view/6424Цель

Цель. Определить воспроизводимость результатов ангиокорегистрации моментального резерва кровотока (МРК) у больных ишемической болезнью сердца (ИБС) с многоуровневым и диффузным поражениями коронарных артерий (КА).

Материал и методы

Материал и методы. В исследование включены 34 пациента хронической ИБС с диффузными и/или многоуровневыми коронарными стенозами >50%. В 41 коронарной артерии выполнены две подряд обратные протяжки проводника и сформированы парные ангиокорегистрации МРК отображающие изменение градиентов МРК (ΔМРК) по всей длине исследованной артерии. Для сопоставления результатов парных исследований использовались полученные значения: 1) индексы дистальных МРК; 2) максимальные ΔМРК; 3) ΔМРК всех стенозов ˃50%.

Результаты

Результаты. Получены сопоставимые значения дистальных МРК (0,84 [0,78; 0,89] против 0,85 [0,77; 0,88]) с средней разницей первого и второго измерений 0,001, максимальных ΔМРК (0,08 [0,05; 0,14] против 0,08 [0,05; 0,13]) с средней разницей −0,004 и ΔМРК всех стенозов >50% (0,05 [0,02; 0,11] против 0,05 [0,02; 0,10]) с средней разницей −0,001. Коэффициенты конкордации Лина и внутриклассовой корреляции, рассчитанные для трех исследованных параметров, показали хороший уровень согласованности (0,97; 0,98; 0,98) с превосходной надежностью (0,97; 0,98; 0,97).

Заключение

Заключение. У больных с многоуровневыми и диффузными поражениями КА ангиокорегистрация МРК обладает достаточно высокой воспроизводимостью.

Aim

Aim. To determine the reproducibility of the results of instantaneous wavefree ratio (iFR) and angiography coregistration in patients with coronary heart disease (CAD) with multilevel and diffuse lesions of the coronary arteries.

Materials and methods

Materials and methods. The study included 34 patients with chronic ischemic heart disease (CAD) with diffuse and/or multilevel coronary stenoses >50%. In 41 coronary arteries, two consecutive iFR pullback of the conductor were performed and paired iFR angio-coregistrations were formed, reflecting changes in iFR gradients (Δ iFR) along the entire length of the studied artery. To compare the results of paired studies, the following values were used: 1) indices of distal iFR; 2) maximum Δ iFR; 3) Δ iFR of all stenoses ˃50%.

Results

Results. Comparable values of distal iFR were obtained 0,84 [0,78; 0,89] vs. 0,85 [0,77; 0,88]) with an average difference of the first and second measurements of 0,001, maximum ΔiFR (0,08 [0,05; 0,14] vs. 0,08 [0,05; 0,13]) with a mean difference of -0,004 and ΔiFR of all stenoses >50% (0,05 [0,02; 0,11] vs. 0,05 [ 0,02; 0,10]) with an average difference of -0.001. Lin’s concordance correlation coefficient and Intraclass Correlation Coefficients calculated for the three parameters studied showed a good level of agreement (0,97; 0,98; 0,98) with excellent reliability (0,97; 0,98; 0,97).

Conclusion

Conclusion. In patients with multilevel and diffuse lesions of the coronary artery, iFR angio-coregistration has a fairly high reproducibility.

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The authors declare that there are no conflicts of interest present.