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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">evrazkar</journal-id><journal-title-group><journal-title xml:lang="ru">Евразийский Кардиологический Журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Eurasian heart journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2225-1685</issn><issn pub-type="epub">2305-0748</issn><publisher><publisher-name>Евразийская ассоциация кардиологов</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.38109/2225-1685-2023-1-66-76</article-id><article-id custom-type="elpub" pub-id-type="custom">evrazkar-6366</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL PAPERS</subject></subj-group></article-categories><title-group><article-title>Индекс массы тела – с позиции оценки состояния больных ишемической болезнью сердца</article-title><trans-title-group xml:lang="en"><trans-title>Body mass index – from the position of assessment of the condition of patients with ischemic heart disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8643-0201</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нагаева</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nagaeva</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нагаева Гульнора Анваровна, кандидат медицинских наук, врач-кардиолог, </p><p>ул. Алмазар, 4, г. Ташкент 100027</p></bio><bio xml:lang="en"><p>Gulnora A. Nagayeva, Cand. of Sci. (Med.), cardiologist</p><p>Almazar St., 4, Tashkent 100027</p></bio><email xlink:type="simple">nagaeva.gulnora@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Журалиев</surname><given-names>М. Ж.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhuraliev</surname><given-names>M. Zh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Журалиев Музаффар Журалиевич, руководитель отделения ангиографии и кардиологии, рентгенэндоваскулярный хирург</p><p>ул. Алмазар, 4, г. Ташкент 100027</p></bio><bio xml:lang="en"><p>Muzaffar Zh. Zhuraliev, Head of the department. Angiography and cardiology, X-ray endovascular surgeon</p><p>Almazar St., 4, Tashkent 100027</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юлдошев</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Yuldoshev</surname><given-names>N. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юлдошев Набижон Пиримович, доктор медицинских наук, руководитель отдела рентгенэндоваскулярной хирургии</p><p>ул. Кичик Халка Йули, 5 А, г. Ташкент 100211</p></bio><bio xml:lang="en"><p>Nabizhon P. Yuldoshev, Dr. of Sci. (Med.), Head of Department X-ray endovascular surgery</p><p>st. Kichik Halka Yuli, 5 A, Tashkent 100211</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ли</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Li</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ли Василий Никитович, главный врач, заведующая отделением реанимации и интенсивной терапии</p><p>ул. Алмазар, 4, г. Ташкент 100027</p></bio><bio xml:lang="en"><p>Vasily N. Li, Chief Physician and Head of the department of Resuscitation and Intensive Care</p><p>Almazar St., 4, Tashkent 100027</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Олимов</surname><given-names>Х. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Olimov</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Олимов Хасан Акмалевич, рентгенэндоваскулярный хирург</p><p>ул. Алмазар, 4, г. Ташкент 100027</p></bio><bio xml:lang="en"><p>Khasan A. Olimov, X-ray endovascular surgeon</p><p>Almazar St., 4, Tashkent 100027</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>СП ООО многопрофильный медицинский центр «Ezgu Niyat»</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>JV LLC Multidisciplinary Medical Center «Ezgu Niyat»</institution><country>Uzbekistan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>AKFA MEDLINE ООО</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>AKFA MEDLINE LLC</institution><country>Uzbekistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>01</day><month>03</month><year>2023</year></pub-date><volume>0</volume><issue>1</issue><fpage>66</fpage><lpage>76</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Нагаева Г.А., Журалиев М.Ж., Юлдошев Н.П., Ли В.Н., Олимов Х.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Нагаева Г.А., Журалиев М.Ж., Юлдошев Н.П., Ли В.Н., Олимов Х.А.</copyright-holder><copyright-holder xml:lang="en">Nagaeva G.A., Zhuraliev M.Z., Yuldoshev N.P., Li V.N., Olimov K.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.heartj.asia/jour/article/view/6366">https://www.heartj.asia/jour/article/view/6366</self-uri><abstract><sec><title>Цель</title><p>Цель: сравнительный анализ клинико-лабораторных и ангиографических показателей у больных ИБС в зависимости от уровня индекса массы тела (ИМТ).</p></sec><sec><title>Материал и методы</title><p>Материал и методы: обследован 71 больной ИБС. Всем проведены общеклинические лабораторно-функциональные исследования и коронароангиография со стентированием коронарных артерий. В зависимости от уровня ИМТ были выделены 2 группы больных: 1 гр. – 36 больных с ИМТ &lt; 30 кг/м2 и 2 гр. – 35 больных с ИМТ ³ 30 кг/м2.</p></sec><sec><title>Результаты</title><p>Результаты: увеличение уровня ИМТ ассоциировалось с молодым возрастом и женским полом, но ме́ньшим количеством острых форм ИБС. Уровень ИМТ ³ 30 кг/м2 характеризовался бóльшей коморбидностью, при этом из сопутствующих патологий чаще отмечались АГ; СД; заболевания ГДЗ (р&lt;0,05); ХОБЛ и перенесённый в анамнезе Covid-19. Кроме того, среди больных с ИМТ ³ 30 кг/м2 частота встречаемости сложных желудочковых нарушений ритма сердца была в 4 раза выше, чем у больных с ИМТ &lt; 30 кг/м2. У больных с ИМТ ³ 30 кг/м2 среднее количество принимаемых в сутки медикаментов было на 0,8 меньше, чем в группе сравнения. Наиболее часто принимаемыми группами ЛП (помимо БАБ и АСКпрепаратов) среди больных 2 группы оказались: АК; сартаны и гипогликемические ЛП, а среди больных 1 группы – иАПФ; статины; тиенопиридины и антиаритмики. 8,5% обследованных оказались не приверженными к медикаментозному лечению, при этом среди больных 1 группы – 13,9% и из 2 группы – 2,8% пациентов. Повышение уровня ИМТ по данным ЭКГ характеризовалось увеличением ЧСС и бо́льшей предрасположенностью к желудочковой аритмии, а по данным ЭхоКГ – утолщением стенок ЛЖ и снижением его систолической функции. Ангиографически бóльшие значения ИМТ не явились критерием сложности сосудистых поражений. Тем не менее, длина атеросклеротического поражения у больных 2 группы была больше, чем у лиц в 1 группе (р&gt;0,05). У больных с ИМТ ³ 30 кг/м2 сравнительно чаще регистрировались поражения дистальных сегментов основных венечных артерий, при этом в бассейне ПНА превалировал стеноз типа В (60,0%), а в бассейне ПКА – стенозы типа А (31,6%) и типа В (47,4%).</p></sec><sec><title>Заключение</title><p>Заключение: в вопросах по оценке взаимосвязи избыточного веса с сердечно-сосудистой патологией еще много спорных моментов. Тем не менее, значимость показателя ИМТ имеет свои прерогативы в этом направлении, особенно в первичном звене </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose: comparative analysis of clinical, laboratory and angiographic parameters in patients with coronary artery disease, depending on the level of body mass index (BMI).</p></sec><sec><title>Material and Methods</title><p>Material and Methods: 71 patients with coronary artery disease were examined. All underwent general clinical laboratory functional studies and coronary angiography with stenting of the coronary arteries. Depending on the level of BMI, 2 groups of patients were identified: 1 gr. – 36 patients with BMI &lt; 30 kg/m2 and 2 gr. – 35 patients with BMI ³ 30 kg/m2.</p></sec><sec><title>Results</title><p>Results: an increase in BMI was associated with young age and female sex, but fewer acute forms of coronary artery disease. The level of BMI ³ 30 kg/m2 was characterized by greater comorbidity, with AH being more frequent among comorbidities; diabetes; diseases of the gastroduodenal zone GDZ (p &lt; 0,05); COPD and past history of Covid-19. In addition, among patients with a BMI ³ 30 kg/m2, the incidence of complex ventricular cardiac arrhythmias was 4 times higher than in patients with a BMI &lt; 30 kg/m2. In patients with BMI ³ 30 kg/m2, the average amount of medications taken per day was 0,8 less than in the comparison group. The most frequently taken groups of drugs (in addition to BAB and ASA drugs) among patients in group 2 were: calcium antagonists AK; sartans and hypoglycemic drugs, and among patients of group 1 – ACE inhibitors; statins; thienopyridines and antiarrhythmics. 8,5% of the surveyed were NOT adherent to drug treatment, while among patients in group 1 – 13,9% and in group 2 – 2,8% of respondents. An increase in BMI according to ECG data was characterized by an increase in heart rate and a greater predisposition to ventricular arrhythmia, and according to echocardiography, by a thickening of the LV walls and a decrease in its systolic function. Angiographically, higher BMI values were not a criterion for the complexity of vascular lesions. Nevertheless, the length of the atherosclerotic lesion in the respondents in group 2 was greater than in group 1 (p &gt; 0,05). In patients with BMI ³ 30 kg/m2, lesions of the distal segments of the main coronary arteries were recorded comparatively more often, with type B stenosis prevailing in the PNA basin (60,0%); in the RCA basin – type A (31,6%) and type B (47,4%) stenoses.</p></sec><sec><title>Conclusion</title><p>Conclusion: there are still many controversial points in the assessment of the relationship between excess weight and cardiovascular pathology. Nevertheless, the significance of the BMI indicator has its prerogatives in this direction, especially in primary health care at the first contact with a patient.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>индекс массы тела</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>коронарография</kwd><kwd>приверженность к лечению</kwd><kwd>коморбидность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>body mass index</kwd><kwd>coronary heart disease</kwd><kwd>coronary angiography</kwd><kwd>adherence to treatment</kwd><kwd>comorbidity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Шпагина О.В., Бондаренко И.З. «Парадокс ожирения» – еще один взгляд на проблему сердечно-сосудистых заболеваний. Ожирение и метаболизм, 4, 2013: с.3-9. doi: 10.14341/OMET201343-9</mixed-citation><mixed-citation xml:lang="en">Shpagina O.V., Bondarenko I.Z. 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