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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">evrazkar</journal-id><journal-title-group><journal-title xml:lang="ru">Евразийский Кардиологический Журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Eurasian heart journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2225-1685</issn><issn pub-type="epub">2305-0748</issn><publisher><publisher-name>Евразийская ассоциация кардиологов</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.38109/2225-1685-2015-3-32-37</article-id><article-id custom-type="elpub" pub-id-type="custom">evrazkar-5644</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL PAPERS</subject></subj-group></article-categories><title-group><article-title>МЕСТО СЕРЕЛАКСИНА В ЛЕЧЕНИИ ОСТРОЙ ДЕКОМПЕНСАЦИИ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ: ОТ УМЕНЬШЕНИЯ СИМПТОМАТИКИ К УЛУЧШЕНИЮ ПРОГНОЗА</article-title><trans-title-group xml:lang="en"><trans-title>SERELAXIN IN THE STRATEGY OF MANAGEMENT THE PATIENTS WITH ACUTE DECOMPENSATED HEART FAILURE: FROM DECREASING OF SYMPTOMS TO THE IMPROVEMENT OF SURVIVAL</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жиров</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhirov</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">izhirov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терещенко</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Tereschenko</surname><given-names>S. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НИИ кардиологии им. А.Л. Мясникова ФГБУ «Российского кардиологического научно-производственного комплекса» МЗ РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Cardiology Research and Production Complex Ministry of Health</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2015</year></pub-date><volume>0</volume><issue>3</issue><fpage>32</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Жиров И.В., Терещенко С.Н., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Жиров И.В., Терещенко С.Н.</copyright-holder><copyright-holder xml:lang="en">Zhirov I.V., Tereschenko S.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.heartj.asia/jour/article/view/5644">https://www.heartj.asia/jour/article/view/5644</self-uri><abstract><p>В обзоре представлены результаты основных клинических исследований препарата серелаксин - первого лекарственного средства для пациентов с острой сердечной недостаточностью, применение которого в острый период ведёт к улучшению среднесрочного прогноза.</p></abstract><trans-abstract xml:lang="en"><p>In this review data of clinical investifation of serelaxin were briefly outlined. In these trials administration of serelaxin just after admission in the hospitals was acoompanied by middle-term improvement of survival of patients with acute heart failure.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>acute decompensated heart failure</kwd><kwd>serelaxine</kwd><kwd>сердечная недостаточность</kwd><kwd>острая декомпенсация</kwd><kwd>серелаксин</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Mebazaa A., Yilmaz M., Levy Ph. et al. Recommendations on pre-hospital and early hospital management of acute heart failure: a consensus paper from the Heart Failure Association of the European Society of Cardiology, the European Society of Emergency Medicine and the Society of Academic Emergency Medicine - short version. Eur Heart J 2015 DOI 10.1093</mixed-citation><mixed-citation xml:lang="en">Mebazaa A., Yilmaz M., Levy Ph. et al. 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