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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">evrazkar</journal-id><journal-title-group><journal-title xml:lang="ru">Евразийский Кардиологический Журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Eurasian heart journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2225-1685</issn><issn pub-type="epub">2305-0748</issn><publisher><publisher-name>Евразийская ассоциация кардиологов</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.38109/2225-1685-2013-1-57-67</article-id><article-id custom-type="elpub" pub-id-type="custom">evrazkar-5540</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL PAPERS</subject></subj-group></article-categories><title-group><article-title>РАСШИРЕННЫЕ ВОЗМОЖНОСТИ ПРИМЕНЕНИЯ КОЭНЗИМА Q10 У БОЛЬНЫХ СЕРДЕЧНО-СОСУДИСТЫМИ ЗАБОЛЕВАНИЯМИ</article-title><trans-title-group xml:lang="en"><trans-title>ADVANCED USE OF COENZYME Q10 IN PATIENTS WITH CARDIOVASCULAR DISEASES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мартынов</surname><given-names>Анатолий Иванович</given-names></name><name name-style="western" xml:lang="en"><surname>Martynov</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гороховская</surname><given-names>Галина Николаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Gorohovskaya</surname><given-names>G. N.</given-names></name></name-alternatives><email xlink:type="simple">yun-vika@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юн</surname><given-names>Виктория Львовна</given-names></name><name name-style="western" xml:lang="en"><surname>Yun</surname><given-names>V. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барвинский</surname><given-names>Александр Андреевич</given-names></name><name name-style="western" xml:lang="en"><surname>Barvinskiy</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петина</surname><given-names>Мария Михайловна</given-names></name><name name-style="western" xml:lang="en"><surname>Petina</surname><given-names>M. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО Московский Государственный Медико-Стоматологический Университет им. А.И. Евдокимова Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M. D. A. I. Evdokimov Moscow State Medical and Dental University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБОУ ВПО Московский Государственный Медико-Стоматологический Университет им. А.И. Евдокимова Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital № 40</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Городская Клиническая Больница № 40</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital № 40</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2013</year></pub-date><volume>0</volume><issue>1</issue><fpage>57</fpage><lpage>67</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мартынов А.И., Гороховская Г.Н., Юн В.Л., Барвинский А.А., Петина М.М., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Мартынов А.И., Гороховская Г.Н., Юн В.Л., Барвинский А.А., Петина М.М.</copyright-holder><copyright-holder xml:lang="en">Martynov A.I., Gorohovskaya G.N., Yun V.L., Barvinskiy A.A., Petina M.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.heartj.asia/jour/article/view/5540">https://www.heartj.asia/jour/article/view/5540</self-uri><abstract><p>В данном обзоре рассматривается интерес к соединениям, которые в обычных условиях предотвращают токсическое действие активных форм кислорода (АФК), - антиоксидантам, а именно о восстановленном убихиноне, который является единственным липидорастворимым антиоксидантом, синтезируемым в клетках животных и человека, а также постоянно регенерируемым из окисленной формы с помощью ферментных систем организма; к возможностям применения коэнзима Q10 при сердечно-сосудистых заболеваниях, оказывающего благоприятное терапевтическое воздействие на организм, что выражается в улучшении работы сердечно-сосудистой, иммунной системы, существенном улучшении состояния в реабилитационным периоде, значительном повышении энергетики организма; к применению коэнзима Q10, в том числе и в детской кардиологии, и изучению его эффективности при первичных и вторичных митохондриальных дефектах, как средства адьювантной терапии таких заболеваний и патологических состояний, как вегетативная дистония, диабетическая кардионейропатия, миокардиодистрофии, артериальная гипертензия, метаболический синдром, постгипоксическая кардиопатия новорожденных, хроническое легочное сердце, гиперлипидемии, период восстановления после кардиохирургической коррекции врожденных пороков сердца, миниинвазивной коррекции аритмий и имплантации ЭКС и др.</p></abstract><trans-abstract xml:lang="en"><p>This report examines interest in compounds that normally prevent the toxic effects of ROS -antioxidants, namely reduced ubiquinone, which is only lipid soluble antioxidant synthesized in cells of animals and humans, and continuously recovered from oxidized form by enzyme systems of the body, to possibilities of the use of coenzyme Q10 in cardiovascular diseases, has a beneficial therapeutic effect on the body, resulting in improvement of the cardiovascular, immune system, significant improvement in rehabilitation period, a significant increase in body energy, the use of coenzyme Q10, including in pediatric cardiology and study its effectiveness in primary and secondary mitochondrial defects as a means of adjuvant therapy of diseases and pathological conditions, as vegetative dystonia, diabetic kardioneyropatiya, myocardial dystrophy, hypertension, metabolic syndrome, cardiomyopathy posthypoxic newborn, chronic pulmonary heart, hyperlipidemia, the recovery period after cardiac correction of congenital heart disease, minimally invasive correction of arrhythmias and pacemaker implantation, etc. reperfusion syndrome, ischemia, hypertension, heart disease, aging, childhood.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Коэнзим Q10</kwd><kwd>убихинон</kwd><kwd>антиоксидант</kwd><kwd>атеросклероз</kwd><kwd>инфаркт миокарда</kwd><kwd>реперфузионный синдром</kwd><kwd>ишемия</kwd><kwd>артериальная гипертония</kwd><kwd>сердечная недостаточность</kwd><kwd>старение</kwd><kwd>детский возраст</kwd><kwd>Coenzyme Q10</kwd><kwd>ubiquinone</kwd><kwd>antioxidant</kwd><kwd>atherosclerosis</kwd><kwd>myocardial infarction</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bagchi D., Sen C.K., Ray S.D., Das D.K., Bagchi M., Preuss H.G., Vinson J.A. 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