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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">evrazkar</journal-id><journal-title-group><journal-title xml:lang="ru">Евразийский Кардиологический Журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Eurasian heart journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2225-1685</issn><issn pub-type="epub">2305-0748</issn><publisher><publisher-name>Евразийская ассоциация кардиологов</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.38109/2225-1685-2019-2-64-75</article-id><article-id custom-type="elpub" pub-id-type="custom">evrazkar-331</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>КЛИНИКО-ИНСТРУМЕНТАЛЬНАЯ ОЦЕНКА МОРФО-ФУНКЦИОНАЛЬНОГО СОСТОЯНИЯ СЕРДЦА И СОСУДОВ ПРИ КОМОРБИДНОСТИ АГ И СД-2</article-title><trans-title-group xml:lang="en"><trans-title>CLINICAL AND INSTRUMENTAL ASSESSMENT OF MORPHO-FUNCTIONAL CONDITION OF THE HEART AND VASCULATURE IN COMORBIDITY OF ARTERIAL HYPERTENSION AND DIABETES MELLITUS TYPE 2</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабаева</surname><given-names>Н. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Babayeva</surname><given-names>N. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>докторант (аспирант)</p><p>Телефон: +994125646978</p><p>Улица Фатали Хан Хойски, 101а, Баку, Азербайджан AZ1072</p></bio><bio xml:lang="en"><p>докторант (аспирант)</p><p>Телефон: +994125646978</p><p>Улица Фатали Хан Хойски, 101а, Баку, Азербайджан AZ1072</p></bio><email xlink:type="simple">nigarbabayeva1985@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский Институт Кардиологии им. акад. Д. Абдуллаева</institution><country>Азербайджан</country></aff><aff xml:lang="en"><institution>Scientific-research institute of cardiology named after C.Abdullayev</institution><country>Azerbaijan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2019</year></pub-date><volume>0</volume><issue>2</issue><fpage>64</fpage><lpage>75</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бабаева Н.З., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Бабаева Н.З.</copyright-holder><copyright-holder xml:lang="en">Babayeva N.Z.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.heartj.asia/jour/article/view/331">https://www.heartj.asia/jour/article/view/331</self-uri><abstract><p>Целью данного исследования являлось изучение морфофункционального состояния сердца и сосудов шеи и липидного спектра у больных артериальной гипертензией (АГ) и сахарным диабетом 2-го типа (СД-2).</p><sec><title>Материал и методы</title><p>Материал и методы. В исследование вошли 144 больных, с различными степенями АГ, 103 имели изолированную АГ, а у 41 больных АГ диагностировалась СД-2. Таким образом, были выделены две подгруппы сравнения: АГ и АГ+СД2. Всем больным была проведена оценка показателей липидного спектра, эхокардиографическое исследование сердца и ультразвуковое дуплексное сканирование сонных артерий.</p></sec><sec><title>Результаты</title><p>Результаты. Результаты проведенного исследования продемонстрировали достоверные различия между подгруппами АГ и АГ+СД2, что подтвердило значительное влияние СД-2 на различные параметры сердечно-сосудистой системы. Изучение липидного профиля в вышеупомянутых подгруппах не показало значительных различий, но подгруппа с СД-2 имело превосходство по некоторым показателям в сравнении с изолированной подгруппой АГ (ТГ, ЛПВП, ЛПОНП). Выраженные изменения эхокардиографических показателей, такие как низкий ФВ ЛЖ, значительное утолщение ТМЖП и ТЗСЛЖ, высокая частота выявления ГЛЖ, диастолической дисфункции, диффузного гипокинеза и дилатации полостей сердца в подгруппе с СД-2 были подтверждены в собственном исследовании. По результатам ультразвукового дуплексного сканирования сонных артерий, недостоверно повышенный ТКИМ было выявлено в подгруппе с СД-2 в сравнении с изолированной подгруппой АГ, что доказало выраженность сосудистых изменений в данной подгруппе больных.</p></sec><sec><title>Заключение</title><p>Заключение. Результаты проведенного исследования подтверждают роль и значимость СД-2 в усугублении патологических изменений сердца и сосудов наряду с АГ.</p></sec></abstract><trans-abstract xml:lang="en"><p>The aim of this study was to investigate the heart and common carotid arteries (CCA) morphological and functional condition and the lipid spectrum in patients with arterial hypertension (AH) and type 2 diabetes mellitus (DM-2).</p><sec><title>Material and methods</title><p>Material and methods. The study included 144 patients with varying degrees of AH, 103 had AH without DM-2 (AH subgroup) and 41 patients with AH and DM-2 (AH+DM-2 subgroup). In all investigated patients the blood plasma lipid profile, echocardiographic examination of the heart and ultrasound Doppler examination of the CCA were carried out.</p></sec><sec><title>The results</title><p> The results. Significant differences between the AH and AH+DM-2 subgroups were discovered, which confirmed the significant effect of DM-2 on various parameters of the cardiovascular system. The lipid profile in the above mentioned subgroups has not significant differences, but some separated indices (TG, VLDL) in the AH+DM-2 subgroup were comparatively higher and HDL level lower comparing to AH subgroup. Marked changes in echocardiographic parameters, such as lowering of left ventricle (LV) ejection fraction (EF), significant increase of interventricular septum and LV posterior wall thickness, high frequency of LV hypertrophy detection, diastolic dysfunction, diffuse hypokinesis and dilatation of the heart cavities in the AH+DM-2 subgroup were confirmed. A significant rise of CCA intima-media thickness also was found in the AH+DM-2 in comparison with AH subgroup, which proved the essential role of comorbidity of AH and DM-2 in the heart and vessels remodeling.</p></sec><sec><title>The conclusion</title><p> The conclusion. The results of the study confirm the role and significance of comorbidity of AH with DM-2 in the development of the cardiovascular system pathological changes.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>сахарный диабет</kwd><kwd>ультразвуковое дуплексное сканирование</kwd><kwd>сонные артерии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Arterial hypertension</kwd><kwd>diabetes mellitus type 2</kwd><kwd>ultrasound dopplerography</kwd><kwd>common carotid arteries</kwd><kwd>lipid exchange</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Рекомендации Европейского общества кардиологов и Европейского общества по артериальной гипертонии, 2018;</mixed-citation><mixed-citation xml:lang="en">Recommendations of the European Society of Cardiology and the European Society of Arterial Hypertension, 2018;</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">GBD 2017 Risk Factor Collaborators. 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