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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">evrazkar</journal-id><journal-title-group><journal-title xml:lang="ru">Евразийский Кардиологический Журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Eurasian heart journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2225-1685</issn><issn pub-type="epub">2305-0748</issn><publisher><publisher-name>Евразийская ассоциация кардиологов</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.38109/2225-1685-2017-4-100-109</article-id><article-id custom-type="elpub" pub-id-type="custom">evrazkar-262</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL PAPERS</subject></subj-group></article-categories><title-group><article-title>НЕПОСРЕДСТВЕННЫЕ РЕЗУЛЬТАТЫ ОТСРОЧЕННЫХ ЧРЕСКОЖНЫХ КОРОНАРНЫХ ВМЕШАТЕЛЬСТВ У БОЛЬНЫХ С ОСТРЫМ КОРОНАРНЫМ СИНДРОМОМ</article-title><trans-title-group xml:lang="en"><trans-title>IMMEDIATE RESULTS OF DELAYED PERCUTANEOUS CORONARY INTERVENTIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чевгун</surname><given-names>С. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Chevgun</surname><given-names>S. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-рентгенхирург</p><p>Бишкек, ул. Энергетиков, 4/73, 720000,</p><p>тел: +996550177377</p></bio><bio xml:lang="en"><p>MD, Endovascular surgeon</p><p>720000, Bishkek, Energetikov str., 4/73</p><p>tel.: +996550177377</p></bio><email xlink:type="simple">schevgun@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдылдаев</surname><given-names>И. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Abdyldaev</surname><given-names>I. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., заведующий отделением РХиОКС,</p><p>720075, г. Бишкек, Микрорайон 8, д. 11, кв. 49</p><p>тел: +996700333190</p></bio><bio xml:lang="en"><p>MD, Head of Department of ES</p><p>720075, Bishkek, Microdistrict 8, Building 11, Apt. 49</p><p>tel.: +996700333190</p></bio><email xlink:type="simple">abdyldaev_ildar@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Данияров</surname><given-names>Б. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Daniyarov</surname><given-names>B. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., врач-рентгенхирург</p><p> 720000, г. Бишкек, ул. Раззакова, 10/7</p><p>тел: +996707659962</p></bio><bio xml:lang="en"><p>MD, Endovascular surgeon</p><p>720000, Bishkek, Razzakova str., 10/7</p><p>tel.: +996707659962</p></bio><email xlink:type="simple">bektur_d@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бадраклы</surname><given-names>Э. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Badrakly</surname><given-names>E. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., заведующий отделением кардиологии,</p><p>720000, г. Бишкек, ул. Джантошева, 117</p><p>тел: +996555909329</p></bio><bio xml:lang="en"><p>MD, Head of Department of Cardiology</p><p>720000, Bishkek, Dzhantosheva str., 117</p><p>tel.: +996555909329</p></bio><email xlink:type="simple">elya57@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осмонов</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Osmonov</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрой «Общей и Факультетской хирургии»</p><p>720060, г. Бишкек, Асанбай, 11-48</p><p>тел: +996772574412</p></bio><bio xml:lang="en"><p>MD, prof., Head of Department «General and faculty surgery»</p><p>720060, Bishkek, Asanbay str., 11-48</p><p>tel.: +996772574412</p></bio><email xlink:type="simple">talgat_ais@rambler.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-Исследовательский Институт Хирургии Сердца и Трансплантации Органов МЗ КР</institution><country>Кыргызстан</country></aff><aff xml:lang="en"><institution>Scientific-Research Institute of Heart Surgery and Organs Transplantation</institution><country>Kyrgyzstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГКБ № 6</institution><country>Кыргызстан</country></aff><aff xml:lang="en"><institution>State Clinical Hospital No.6</institution><country>Kyrgyzstan</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Кыргызско-Российский Славянский Университет</institution><country>Кыргызстан</country></aff><aff xml:lang="en"><institution>Kyrgyz-Russian Slavic University</institution><country>Kyrgyzstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2017</year></pub-date><volume>0</volume><issue>4</issue><fpage>100</fpage><lpage>109</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чевгун С.Д., Абдылдаев И.З., Данияров Б.С., Бадраклы Э.Ф., Осмонов Т.А., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Чевгун С.Д., Абдылдаев И.З., Данияров Б.С., Бадраклы Э.Ф., Осмонов Т.А.</copyright-holder><copyright-holder xml:lang="en">Chevgun S.D., Abdyldaev I.Z., Daniyarov B.S., Badrakly E.F., Osmonov T.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.heartj.asia/jour/article/view/262">https://www.heartj.asia/jour/article/view/262</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Чрескожные коронарные вмешательства (ЧКВ) давно стали эффективным инструментом в лечении острых коронарных синдромов (ОКС), и своевременность вмешательств у таких пациентов имеет большое значение. Однако, в связи с социально-экономическими трудностями, не всегда возможно проведение адекватного лечения данного острого состояния в соответствии с установленными международными критериями и стандартами, что дает повод исследовать результаты выработанного практической деятельностью подхода к тактике «вынужденно» отсроченных ЧКВ у больных с ОКС.</p><p>Цель исследования состояла в оценке непосредственных результатов отсроченного ЧКВ у пациентов с ОКС.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В исследование были включены пациенты с ОКС, поступившие для прохождения коронароангиографии (КАГ) с возможным стентированием коронарных артерий (КА) («острая» группа ЧКВ, 42 пациента); пациенты, получавшие медикаментозную терапию по поводу ОКС в госпитале без возможности ЧКВ (50 пациентов) и медикаментозно стабилизированные пациенты после ОКС, которые поступили для КАГ и стентирования КА (в среднем через 30 дней после ОКС, 49 пациентов). Группы не отличались базовыми демографическими и клиническими характеристиками. Были оценены стандартные клинические, электрокардиографические (ЭКГ) и эхокардиографические (ЭХОкг) данные.</p></sec><sec><title>Результаты</title><p> Результаты. В группах ЧКВ ангиографический успех был достигнут в 100% случаев. Среднее время от появления симптомов до ЧКВ в «острой» группе составляло 89,4 часов. В «острой» группе смертность составила 3 пациента (7,1%), а в группе медикаментозной терапии смертность составила 18% (р&lt;0,05). Среди умерших в «острой» группе два пациента имели кардиальные причины и в момент прибытия у них наблюдалась симптоматика кардиогенного шока, один пациент умер от осложнений, вызванных большим кровотечением. Положительная динамика возвращения сегмента ST на ЭКГ и показателей ЭХОкг была более выражена в «острой» группе ЧКВ.</p></sec><sec><title>Заключение</title><p>Заключение. Несмотря на задержку во времени, ЧКВ при ОКС является более эффективным методом восстановления функции миокарда даже по сравнению с пациентами, которые получали ранний тромболизис.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective. Percutaneous coronary interventions (PCI) have long been an effective tool in the treatment of acute coronary syndromes (ACS), and timely interventions in such patients have great importance. However, due to socio-economic difficulties, it is not always possible to treat adequately this acute condition, in accordance with established international criteria. This gives an opportunity to investigate the results of the practical approach to delayed percutaneous coronary interventions in patients with acute coronary syndrome.</p></sec><sec><title>Purpose</title><p>Purpose. Evaluate the immediate results of delayed percutaneous coronary interventions in patients with acute coronary syndrome.</p></sec><sec><title>Methods</title><p>Methods. In this study were included patients with ACS who received coronary angiography with stenting of coronary arteries («acute» PCI group, 42 patients), patients who were treated by medical therapy for ACS in the hospital without possibility of PCI (50 patients), and medically stabilized patients after ACS, which were given for angiography and PCI. (average, 30 days after ACS, 49 patients). The groups did not differ in basic demographic and clinical characteristics. Standard clinical, electrocardiographic (ECG) and echocardiographic (ECH0) data were evaluated.</p></sec><sec><title>Results</title><p>Results. In the PCI groups, angiographic success was achieved in 100%. The average time from the symptoms onset to PCI in the «acute» group was 89.4 hours. In the «acute» group, mortality was 3 patients (7.1%), and in the medical therapy group, mortality was 18% (p &lt;0,05). In the «acute» group two patients had cardiac adverse events, and at presented they had a cardiogenic shock symptoms, one patient died from complications due to major bleeding. The positive dynamics of ST segment recovery on the ECG and ECH0 parameters was more pronounced in the «acute» PCI group.</p></sec><sec><title>Conclusions</title><p>Conclusions. Despite on the time delay, PCI in ACS is more effective method of restoring myocardial function even in comparison with patients who received early thrombolysis.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>чрескожные коронарные вмешательства</kwd><kwd>острый коронарный синдром</kwd></kwd-group><kwd-group xml:lang="en"><kwd>percutaneous coronary interventions</kwd><kwd>acute coronary syndrome</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Steg P.G., James S.K., Atar D. et al. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J 2012; 33(20):2569-619.;</mixed-citation><mixed-citation xml:lang="en">Steg P.G., James S.K., Atar D. et al. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J 2012; 33(20):2569-619.;</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Gershlick A.H., Banning A.P., Myat A. et al. Reperfusion therapy for STEMI: is there still a role for thrombolysis in the era of primary percutaneous coronary intervention? Lancet 2013; 382(9892):624-32.</mixed-citation><mixed-citation xml:lang="en">Gershlick A.H., Banning A.P., Myat A. et al. Reperfusion therapy for STEMI: is there still a role for thrombolysis in the era of primary percutaneous coronary intervention? Lancet 2013; 382(9892):624-32.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Boersma E., Maas A.C., Deckers J.W., Simoons M.L. Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour. Lancet 1996; 348(9030):771-5.</mixed-citation><mixed-citation xml:lang="en">Boersma E., Maas A.C., Deckers J.W., Simoons M.L. Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour. Lancet 1996; 348(9030):771-5.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Boersma E. Does time matter? A pooled analysis of randomized clinical trials comparing primary percutaneous coronary intervention and in-hospital fibrinolysis in acute myocardial infarction patients. Eur Heart J 2006; 27(7):779-88.</mixed-citation><mixed-citation xml:lang="en">Boersma E. Does time matter? A pooled analysis of randomized clinical trials comparing primary percutaneous coronary intervention and in-hospital fibrinolysis in acute myocardial infarction patients. Eur Heart J 2006; 27(7):779-88.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Keeley E.C., Boura J.A., Grines C.L. Comparison of primary and facilitated percutaneous coronary interventions for ST-elevation myocardial infarction: quantitative review of randomised trials. Lancet 2006; 367(9510):579-88.</mixed-citation><mixed-citation xml:lang="en">Keeley E.C., Boura J.A., Grines C.L. Comparison of primary and facilitated percutaneous coronary interventions for ST-elevation myocardial infarction: quantitative review of randomised trials. Lancet 2006; 367(9510):579-88.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Mehilli J., Kastrati A, Schulz S. et al. Abciximab in patients with acute ST-segment-elevation myocardial infarction undergoing primary percutaneous coronary intervention after clopidogrel loading: a randomized double-blind trial. Circulation 2009; 119(14):1933-40.</mixed-citation><mixed-citation xml:lang="en">Mehilli J., Kastrati A, Schulz S. et al. Abciximab in patients with acute ST-segment-elevation myocardial infarction undergoing primary percutaneous coronary intervention after clopidogrel loading: a randomized double-blind trial. Circulation 2009; 119(14):1933-40.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Busk M., Kaltoft A., Nielsen S.S. et al. Infarct size and myocardial salvage after primary angioplasty in patients presenting with symptoms for ,12 h vs. 12-72 h. Eur Heart J 2009; 30(11):1322-30.</mixed-citation><mixed-citation xml:lang="en">Busk M., Kaltoft A., Nielsen S.S. et al. Infarct size and myocardial salvage after primary angioplasty in patients presenting with symptoms for ,12 h vs. 12-72 h. Eur Heart J 2009; 30(11):1322-30.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Schomig A., Mehilli J., Antoniucci D. et al. Mechanical reperfusion in patients with acute myocardial infarction presenting more than 12 hours from symptom onset: a randomized controlled trial. JAMA 2005; 293(23):2865-72.</mixed-citation><mixed-citation xml:lang="en">Schomig A., Mehilli J., Antoniucci D. et al. Mechanical reperfusion in patients with acute myocardial infarction presenting more than 12 hours from symptom onset: a randomized controlled trial. JAMA 2005; 293(23):2865-72.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Herrin J., Miller L.E., Turkmani D.F. et al. National performance on door-in to door-out time among patients transferred for primary percutaneous coronary intervention. Arch Intern Med 2011; 171(21):1879-86.</mixed-citation><mixed-citation xml:lang="en">Herrin J., Miller L.E., Turkmani D.F. et al. National performance on door-in to door-out time among patients transferred for primary percutaneous coronary intervention. Arch Intern Med 2011; 171(21):1879-86.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Wang T.Y., Nallamothu B.K., Krumholz H.M. et al. Association of door-in to door-out time with reperfusion delays and outcomes among patients transferred for primary percutaneous coronary intervention. JAMA 2011; 305(24):2540-7.</mixed-citation><mixed-citation xml:lang="en">Wang T.Y., Nallamothu B.K., Krumholz H.M. et al. Association of door-in to door-out time with reperfusion delays and outcomes among patients transferred for primary percutaneous coronary intervention. JAMA 2011; 305(24):2540-7.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Рекомендации ESC/EACTS по реваскуляризации миокарда 2014. Российский кардиологический журнал 2015; 2(118):27-28.</mixed-citation><mixed-citation xml:lang="en">ESC/EACTS recommendations on myocardial revascularization 2014. Russian Cardiology Journal 2015; 2(118): 27-28 [in Russian].</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">McLaughlin M.G., Stone G.W., Aymong E. et al. Prognostic utility of comparative methods for assessment of ST-segment resolution after primary angioplasty for acute myocardial infarction: the Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications (CADILLAC) trial. J Am Coll Cardiol. 2004; 44:1215-1223</mixed-citation><mixed-citation xml:lang="en">McLaughlin M.G., Stone G.W., Aymong E. et al. Prognostic utility of comparative methods for assessment of ST-segment resolution after primary angioplasty for acute myocardial infarction: the Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications (CADILLAC) trial. J Am Coll Cardiol. 2004; 44:1215-1223</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Vakili H., Sadeghi R., Rezapoor P., Gachkar L. In-hospital outcomes after primary percutaneous coronary intervention according to left ventricular ejection fraction. ARYA Atheroscler 2014; 10(4): 211-7.</mixed-citation><mixed-citation xml:lang="en">Vakili H., Sadeghi R., Rezapoor P., Gachkar L. In-hospital outcomes after primary percutaneous coronary intervention according to left ventricular ejection fraction. ARYA Atheroscler 2014; 10(4): 211-7.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
